CD36 Antikörper (APC)

Produktnummer ABIN1449146

Der Maus Monoklonal Anti-CD36-Antikörper wurde für FACS validiert. Er ist geeignet, CD36 in Proben von Human zu detektieren.

Kurzübersicht für CD36 Antikörper (APC) (ABIN1449146)

Target: CD36

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD36 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: CB38 (NL07)

Produktdetails anti-CD36 Antikörper (APC)

Immunogen: Living human myeloid cells

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 15 mM sodium azide, 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE! This products is photosensitive and should be protected from light.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C.

Details zu CD36

Target: CD36

Andere Bezeichnung: CD36

Hintergrund: CD36 (fatty acid translocase, FAT) is an 85-113 kDa ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and it is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similarly to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids.Synonyms: Fatty acid translocase, GP3B, GP4, Glycoprotein IIIb, PAS IV, PAS-4, Platelet collagen receptor, Platelet glycoprotein 4, Platelet glycoprotein IV, Thrombospondin receptor

Gen-ID: 9606

UniProt: P16671

Pathways: TLR Signalweg, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteine